hCSF2RB/hIL3/hCSF2

Nomenclature

C57BL/6Smoc-Csf2rbtm(hCSF2RB)Il3tm(hIL3)Csf2tm(hCSF2)Smoc

Cat. NO.

NM-HU-230239

Strain State

Developing

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Gene Summary

Gene Symbol
IL3

Synonyms

BPA; PSF; HCGF; Il-3; MCGF; Csfmu

NCBI ID

16187

MGI ID

96552

Ensembl ID

ENSMUSG00000018914

Pubmed

IL3

Human Ortholog

IL3

Gene Symbol
CSF2

Synonyms

CSF; Csfgm; GMCSF; Gm-CSf; MGI-IGM

NCBI ID

12981

MGI ID

1339752

Ensembl ID

ENSMUSG00000018916

Pubmed

CSF2

Human Ortholog

CSF2

Gene Symbol
Csf2rb

Synonyms

Bc; Il3r; AIC2B; Il3rb; Il5rb; CDw131; Il3rb1; Csf2rb1; Csfgmrb; AI848964

NCBI ID

12983

MGI ID

1339759

Ensembl ID

ENSMUSG00000071713

Pubmed

Csf2rb

Human Ortholog

CSF2RB

Model Description

hCSF2RB（NM-HU-225078）was crossed with hIL3/hCSF2（NM-HU-190065）to generate hCSF2RB/hIL3/hCSF2.

Validation Data

image.png

Fig.1 Detection of CSF2RB expression in mammary gland by RT-PCR (6-8wks, female). 

Wild type: only one band at 517 bp with primers F1/R1(mCsf2rb);

Homozygous: only one band at 324 bp with primers F2/R2(hCSF2RB).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hCD131 expression on B cells and Granulocytes in Bone marrow in hCSF2RB/hIL3/hCSF2 tKI mice.

image.png

Fig.3 Detection of hCD131 expression on B cells and Granulocytes in Spleen in hCSF2RB/hIL3/hCSF2 tKI mice.

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