hTL1A(BALB/c)
Nomenclature
BALB/cAnSmoc-Tnfsf15em1(hTNFSF15)Smoc
Cat. NO.
NM-HU-220602
Strain State
Repository Live
Gene Summary
Gene Symbol
Tnfsf15
Model Description
The endogenous mouse Tnfsf15 gene was replaced by human TNFSF15 gene.
Validation Data
Fig.1 Detection of TL1A expression in bladder by RT-PCR.
Wild type: only one band at 285 bp with primers F1/R1 (mTl1a);
Homozygous: only one band at 233 bp with primers F2/R2 (hTL1A).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of hTL1A (A) and mTL1A (B) expression in lung homogenate by ELISA (n=3).
Abbr. HO, homozygous;WT, wild type.
Note. hTL1A and BALB/c mice were i.p. injected with LPS for 6h. The anti-human and mouse TL1A kit cross-reacted with mTL1A and humanized TL1A.
Fig.3 Detection of TL1A expression on endothelial and epithelial cells in lung in hTL1A mice
Note. The hom hTL1A mice were stimulated with LPS in vivo.
You may also like
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreOur vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
Learn more