hCD5(2)
Nomenclature
C57BL/6Smoc-Cd5tm(hCD5)Smoc
Cat. NO.
NM-HU-220579
Strain State
Repository Live
Gene Summary
Gene Symbol
Cd5
Model Description
The endogenous mouse Cd5 gene was replaced by human CD5 gene.
Validation Data
Fig.1 Detection of CD5 expression in thymus by RT-PCR.
Wild type: only one band at 138 bp with primers F1/R1 (mCd5);
Homozygous: only one band at 350 bp with primers F2/R2 (hCD5).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of hCD5 expression in T cells and B cells in Blood in hCD5(2) KI mice.
Fig.3 Detection of hCD5 expression in T cells and B cells in Spleen in hCD5(2) KI mice.
Fig.4 Analysis of leukocytes cell subpopulation in Blood and spleen.
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