hIL6/hIL6R(NMG)
Nomenclature
NOD-PrkdcscidIl2rgem1Il6tm(hIL6)Il6raem(hIL6R)Smoc
Cat. NO.
NM-HU-220427
Strain State
Repository Live
Model Description
The hIL6/hIL6R (NM-HU-190025) mice were backcrossed to NMG genetic background, to create the new strain of hIL6/hIL6R(NMG) (NM-HU-220427) mice.
Validation Data
Fig.1 Detection of hIL-6 expression in serum by ELISA in hIL6/hIL6R(NMG) mice (n=3).
Abbr. HO, homozygous; WT, wild type.
Note. hIL6/hIL6R(NMG) and NMG mice were i.p. injected with LPS for 2h.
Fig 2. Detection of hIL-6R expression on Myeloid cells in spleen in hIL6/hIL6R(NMG) mice.
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