The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-Loxp-Stop-Loxp-Kozak-hIL2 signal peptide-hIL15-Flag-IRES-EGFP-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220130
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-LSL-Kozak-hNTN1-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-233967
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Strain Name：FVB-Gt(ROSA)26Sorem1(pAPOE-CYP3A4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18032
Research Application：metabolism
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Strain Name：FVB-Gt(ROSA)26Sorem1(Gut-CYP3A4-IRES-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18033
Research Application：metabolism
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-loxp-stop-loxp-hMycRTG3-ERT2-IRES-EGFP-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225096
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Strain Name：C57BL/6Smoc-Rab31em1(hRAB31*Y76F/Y86F/Y137F)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210419
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Strain Name：C57BL/6Smoc-Rag2em2Erbb2tm1(hHER2)Smoc
Strain State：Developing | Cat. NO.：NM-HU-234873
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Strain Name：C57BL/6Smoc-Rag2em2Tacstd2em(hTACSTD2)Smoc
Strain State：Developing | Cat. NO.：NM-HU-234872
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Strain Name：C57BL/6Smoc-Kdrtm2(hKDR)Rag2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200280
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Strain Name：C57BL/6Smoc-Cd40em1(hCD40)Rag2em1Il2rgem1/Smoc
Strain State：Developing | Cat. NO.：NM-HU-2000112
Research Application：Immunotherapy,cancer research,drug screening
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