hF12
Nomenclature
C57BL/6Smoc-F12tm1(hF12)/Smoc
Cat. NO.
NM-HU-210017
Strain State
Repository Live
Gene Summary
Gene Symbol
F12
Model Description
The endogenous mice F12 gene was replaced by human F12 gene.
Validation Data
Fig1. Detection of F12 expression in liver by RT-PCR.
Wild type: only one band at 318 bp with primers F1/R1(mF12);
Homozygous: only one band at 274 bp with primers F2/R2(hF12);
Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig.2 Detection of human F12 (A) and mouse F12 (B) expression in serum by ELISA (male, 8-11wks, n=2).
Abbr. HO, homozygous; WT, wild type.
Fig.3 Detection of hF12 expression in serum by ELISA (male, n=3).
Abbr. HO, homozygous; WT, wild type.
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